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Case study

Upperton Pharma Solutions

Trent Gateway

  • £15m

    Total Project Value

  • 4500m2

    Scale

  • 42 weeks

    Turnaround

Following a negotiated tender process, T-SQUARED was appointed as Upperton Pharma’s preferred specialist contracting partner to design and deliver this new large- scale multi-building project development.

Driven by the immediate needs for manufacturing scale-up, together with general business expansion drivers, facility provisions constructed include an expansive GMP cleanroom suite together with associated warehousing, both QA and separate R&D laboratories, as well as a new corporate office headquarter development to house the rising staff numbers. The challenge to deliver over 4500m2 of high-tech pharmaceutical accommodations within record time was embraced by T-SQUARED’s combined design and project management team.

Success was realised through a common vision embraced by both the T-SQUARED and Upperton teams, a collaborative partnership was quickly established and maintained throughout to ensure a non-contractual strategic focus. And through this spirit of openness and trust intermediate delivery milestones were regularly bettered as well as the overall facility being ready ahead of schedule. T-SQUARED’s multi-discipline turnkey expertise ensured that all wider matters of Planning, Building Control and utility upgrade were managed thereby allowing Upperton to retain focus on their day- to-day pharma activity. Internal fit-out works included the provision of new structural plant decks, specialist cleanroom and laboratory finishes, HVAC and mechanical services together with all required electrical and data provisions. As a licensed and regulated facility, MHRA testing compliance was captured through a comprehensive validation life-cycle exercise including DQ, IQ and OQ execution.

The speed of delivery for the size of undertaking has been exceptional. T-SQUARED has impressed at every turn.

Upperton Pharma

Winner – Pharma Industry Awards UK 2024

The Pharma Industry Awards UK celebrates the achievements of the entire pharmaceutical ecosystem – from researchers to CROs, engineers to marketing teams.

T-SQUARED’s GMP manufacturing cleanroom suite, laboratories and warehousing at Trent Gateway for Upperton Pharma Solutions is the overall winner for Large Pharma Project of the Year 2024.

This award is the culmination of 18 months of hard work by our team and design and build vendor, T-SQUARED. To build a facility of this quality within 10 months is an outstanding achievement. To then validate, commission and receive MHRA Approval provided us with a platform to develop and manufacture on a new scale for our customers.

Ian Lafferty

Chief Technical Officer & Project Lead, Upperton Pharma Solutions